Chymase 1, Mast Cell (CMA1) Peptide
CMA1
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN938181
Quick Overview for Chymase 1, Mast Cell (CMA1) Peptide (ABIN938181)
Target
CMA1
(Chymase 1, Mast Cell (CMA1))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- EVKLRLMDPQ ACSHFRDFDH NLQLCVGNPR KTKSAFKGDS GGPLLCAGVA
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of CMA1 antibody,
Alternative Names: CMA1 control peptide, CMA1 antibody Blocking Peptide, Anti-CMA1 Blocking Peptide, chymase 1, mast cell Blocking Peptide, CYH Blocking Peptide, MCT1 Blocking Peptide, MGC119890 Blocking Peptide, MGC119891 Blocking Peptide, chymase Blocking Peptide, CMA1, CMA-1, CMA 1, CMA-1 Blocking Peptide, CMA 1 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- CMA1 (Chymase 1, Mast Cell (CMA1))
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Background
- CMA1 is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies.
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Molecular Weight
- 27 kDa
Target
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